We are mitigating the harmful social determinants of health.
Join our efforts to put an end to health inequities and harmful social determinants of health (SDOH).
We are advancing a nurse-led model of care that can transform health care by expanding access, improving outcomes and lowering costs.
Join our efforts to put an end to health inequities and harmful social determinants of health (SDOH).
We are committed to end health inequities through transformative excellence in education, clinical practice, and nursing science.
Join our efforts to put an end to health inequities and harmful social determinants of health (SDOH).
We are preparing future nurse leaders and scientists to transform health care.
Join our efforts to put an end to health inequities and harmful social determinants of health (SDOH).
8 Defining
SDOH Principles
Discover eight principles about the mechanisms of social determinants of health that can inform your work.
A New Approach
to SDOH Mitigation
Explore our framework for nurse-led programs that can help mitigate the harmful social determinants of health.
Stay updated on the Duke University School of Nursing’s latest efforts to transform health care.
The Importance of Addressing Social Determinants of Health.
If efforts to reduce health inequity are to be successful, new thinking is needed to design and implement more effective programs that can mitigate the harmful social determinants of health.
The DUSON/CLAFH Approach.

In an effort to shift the paradigm, the Center for Latino Adolescent and Family Health (CLAFH) at the Duke University School of Nursing has synthesized the existing research on social determinants of health. Our team identified eight key SDOH principles that should be considered when designing and implementing programs to mitigate harmful social determinants of health.
8 Defining SDOH Principles
A review of landmark research identifies eight key principles about the mechanisms of social determinants of health.


SDOH are Underlying Causes of Health Inequities

SDOH Context Shapes Health Inequities

SDOH Contextual Disadvantage is Not Deterministic

SDOH Shapes Health Over the Life Course

SDOH Operate Through Biological Embedding

SDOH Operate Intergenerationally

SDOH Shapes Clustering and Synergies of Health Inequities

SDOH and Social Injustices Interact to Produce Health Inequities
After clicking each icon to learn more about the eight principles, scroll down to discover how they inform the Duke University School of Nursing (DUSON) Center for Latino Adolescent and Family Health’s (CLAFH) framework for mitigating harmful SDOH.
A new framework for mitigating harmful SDOH
DUSON Trailblazer SDOH Toolkit





